SPEAKERS

Dr. Sharon Nachman

Dr. Sharon Nachman is the IMPAACT Network Chair, the Chief of the Division of Pediatric Infectious Diseases, Director of the Office of Clinical Trials, and Professor of Pediatrics in the School of Medicine at SUNY at Stony Brook, and an Adjunct Professor of Pathology at The Johns Hopkins University School of Medicine. Dr. Nachman is an international leader in the area of pediatric infectious diseases and has been the principal investigator of more than 30 clinical trials of promising medicine for patients in the areas of new vaccines, Lyme disease, and HIV and TB

Dr. Patricia Flynn

Dr. Patricia Flynn is the IMPAACT Network Vice-Chair, Senior Vice President and Medical Director of Quality and Patient Care and Deputy Clinical Director, Member in the Department of Infectious Diseases and the Arthur Ashe Chair in Pediatric AIDS Research at St. Jude Children’s Research Hospital.

Dr. Philippa Musoke

Dr. Philippa Musoke is the IMPAACT Network International Vice-Chair, and Professor of Paediatrics and Child Health in the College of Health Sciences, Makerere University. Dr. Musoke has been conducting research with the Makerere University-Johns Hopkins University research collaboration since 1995, including paediatric HIV treatment clinical trials to improve antiretroviral therapy for children in resource limited settings and paediatric TB diagnostics and treatment. She is also the chair of the Ministry of Health, PMTCT and Paediatric ART technical committees.

Dr. Carl W. Dieffenbach

Dr. Carl W. Dieffenbach is the Director of the Division of AIDS (DAIDS) at the National Institute of Allergy and Infectious Diseases at NIH. Dr. Dieffenbach is responsible for managing DAIDS programs, which include basic laboratory research and clinical trials to develop therapies to treat HIV and related infections and diseases, as well as to develop vaccines, microbicides and other HIV prevention strategies.

Dr. Salim Abdool Karim

Dr. Salim Abdool Karim is a clinical infectious diseases epidemiologist widely recognized for his contributions in both AIDS and Covid-19. He is Director of the Centre for the AIDS Program of Research in South Africa (CAPRISA) and CAPRISA Professor for Global Health at Columbia University. He is an Adjunct Professor in Immunology and Infectious Diseases at Harvard University. He is a member of the WHO Science Council and Chair of the WHO's Scientific and Technical Advisory Group on HIV. He is a member of the African Task Force on Coronavirus. He is a Fellow of the Royal Society.

Dr. Karin Nielsen

Dr. Karin Nielsen is a Professor of Pediatrics in the Division of Infectious Diseases at UCLA Children's Hospital and a member of the UCLA faculty since 1996. She is an attending physician for Pediatric Infectious Diseases at Mattel Children's Hospital and co-director of the Care4Families HIV clinic at UCLA. Dr. Nielsen's main area of research has been pediatric infections particularly in the area of HIV and congenital infections. She is an internationally recognized expert in the field of pediatric HIV and Zika.

Dr. Shahin Lockman

Dr. Shahin Lockman is an Associate Professor of Medicine, Harvard Medical School and BWH Division of Infectious Diseases; and Associate Professor in the Department of Immunology and Infectious Diseases at the Harvard T.H. Chan School of Public Health. She is also one of the CTU principal investigators for the Botswana-Harvard School of Public Health AIDS Initiative Partnership CTU, with sites in Gaborone and Molepolole, Botswana.

Dr. Larry Brown

Dr. Larry Brown is Director of the Division of Child and Adolescent Psychiatry and Vice Chair of the Department of Psychiatry and Human Behavior at Brown University. He has a particular interest in prevention of HIV and risk behaviors among adolescents and young adults. He also conducts clinical treatment trials to reduce substance use and depression for those living with HIV. In addition, his research promotes engagement and adherence to pre-exposure prophylaxis for MSM in the South.

Dr. Lameck Chinula

Dr. Lameck Chinula is Assistant Professor in the Department of Obstetrics and Gynecology’s Division of Global Women’s Health at the University of North Carolina (UNC) at Chapel Hill and a Clinical Research Site Leader at UNC Project Malawi, a collaboration between UNC and Malawi Ministry of Health. He leads UNC Global HIV Clinical Trials Unit Malawi Clinical Research Site participation in HIV prevention and treatment trials and also in NCI AIDS Malignancy Consortium. He is a Co-chair for IMPAACT 2010 study. Dr Chinula is also an honorary lecturer at Kamuzu University of Health Sciences, formerly University of Malawi, College of Medicine. He has research interests in HIV and cervical cancer prevention.

Dr. Risa Hoffman

Dr. Risa Hoffman is Associate Clinical Professor in the Division of Infectious Diseases at UCLA. Dr. Hoffman's research focuses on HIV co-morbidities, as well as on the implementation of HIV service delivery in resource-limited settings. She has performed collaborative research with teams in Malawi, Zambia, South Africa, and Brazil and since 2009 she has served on the leadership team of a large PEPFAR/USAID grant that is a collaboration between Partners in Hope, a nonprofit medical center in Malawi, and the UCLA Division of Infectious Diseases. With IMPAACT, she is an investigator on randomized clinical trials focused on improving clinical treatment strategies for HIV-infected pregnant and postpartum women globally. In addition to research, Dr. Hoffman serves as an Associate Director of the UCLA Infectious Diseases Fellowship Training Program and Director of the Global Health Program for the David Geffen School of Medicine.

Dr. Tapiwa Mbengeranwa

Dr. Tapiwa Mbengeranwa is a Sub-Investigator with the University of Zimbabwe Clinical Trials Research Centre with a keen interest in quality management systems. Based at Harare Family Care Clinical Research Site for the past 13 years, she has implemented a wide variety of Phase I-IV trials under the IMPAACT network. Under her direction, HFC CRS site team contributed over 20% of the study participants enrolled to IMPAACT 2010, 150 mother-infant pairs. In this talk, Dr Mbengeranwa will cover the bone density outcomes for mothers randomized in pregnancy to various ART regimens and their breastfeeding children.

Dr. Elisa López Varela

Dr. Elisa López Varela is an Assistant Research Professor at the Barcelona Institute for Global Health, ISGlobal in Barcelona, Spain. She trained as a physician at the Autonoma University of Madrid, Spain and completed her residency in Pediatrics at Hospital Clinico San Carlos, University Complutense, Madrid, Spain. She received a Master´s Degree in Public Health from Harvard University in Boston before earning a PhD in Translational Medicine at the University of Barcelona (ISGlobal). From 2018 to 2020 she was a postdoctoral fellow at the Desmond Tutu TB Centre, Stellenbosch University, Cape Town, South Africa thanks to a postdoctoral grant from the Ramón Areces Foundation and the Spanish Association of Paediatrics. Dr. Lopez Varela’s scientific interest focuses on assessing and understanding the burden of pediatric TB in Africa and in the development of new diagnostic tools and treatments.

Professor Mark Hatherill

Professor Mark Hatherill is the Director of the South African Tuberculosis Vaccine Initiative (SATVI) at the University of Cape Town. He trained in paediatrics and critical care and has worked in TB research for the last 15 years. His clinical research interests have focused on design, implementation, and analysis of multiple clinical trials of novel TB vaccine candidates in infants, children and adults; as well as translational studies of host biomarkers for triage, diagnosis and prediction of TB disease

Dr. Amita Gupta

Dr. Amita Gupta is Deputy Director of the Johns Hopkins Center for Clinical Global Health Education, Faculty Chair of the Johns Hopkins India Institute and Professor of Infectious Diseases at the JH School of Medicine, with a joint appointment in International Health at the Bloomberg School of Public Health. Dr. Gupta specializes in international public health, clinical research, and education in infectious diseases, HIV/AIDS, tuberculosis (TB), and antimicrobial resistance. Dr. Gupta is also Co-principal Investigator of the NIH-funded Baltimore-India HIV and Infectious Diseases Clinical Trials Unit, and she co-leads the IMPAACT TB Scientific Committee.

Dr. Anneke Hesseling

Dr. Anneke Hesseling a Distinguished Professor in Paediatrics and Child Health in the Department of Paediatrics and Child Health at the Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa, where she is also the Director of the Desmond Tutu TB Centre. She chairs the IMPAACT TB Scientific Committee, leads/co-leads several IMPAACT protocols, and is the PI for the Stellenbosch DAIDS-funded Clinical Trials Unit (SUN-CTU) network and is the IMPAACT CRS leader for the Desmond Tutu TB Centre (DTTC, CRS 31790) I Cape Town. Her group at the Desmond Tutu TB Centre also conducts rigorous epidemiological, implementation science research and socio-behavorial research and has strong collaboration with public health programmes and community stakeholders to advance a family-centered model of research and care for TB or HIV. She is passionate about building capacity for TB clinical research in resource-limited settings.

Dr. Theodore Ruel

Dr. Theodore Ruel is a Professor and Chief of the Division of Pediatric Infectious Disease and Global Health at the University of California San Francisco - Benioff Children's Hospital. Dr. Ruel is co-chair Department of Health and Human Services (HHS) Panel on Antiretroviral Therapy and Medical Management of Children Living with HIV and vice-chair of the Pediatric Antiretroviral Working Group of the WHO. He currently serves as chair of the IMPAACT Treatment Scientific Committee.

Dr. Moherndran Archary

Dr. Moherndran Archary is an associate professor in paediatric infectious disease specialist in the Department of Paediatrics and Child Health at King Edward VIII Hospital affiliated to the University of KwaZulu-Natal and CAPRISA Umlazi CTU. His research interests include antiretroviral drug therapeutics, viral resistance and optimal timing of initiation of antiretroviral therapy in the developing world. He is the Vice-Chair of the IMPAACT Treatment Scientific Committee.

Dr. Charles Flexner

Dr. Charles Flexner is Professor of Medicine in the Divisions of Clinical Pharmacology and Infectious Diseases, and Professor of Pharmacology and Molecular Sciences in the Johns Hopkins University School of Medicine. He is also Professor of International Health in the Johns Hopkins University Bloomberg School of Public Health. Dr. Flexner is an expert on the basic and clinical pharmacology of drugs for HIV/AIDS and related infections, including viral hepatitis and tuberculosis. Dr. Flexner is currently the Chief Scientific Officer of the Institute for Clinical and Translational Research at Johns Hopkins. He is the Co-Principal Investigator of the Johns Hopkins University-India AIDS Clinical Trials Unit (JHUBI CTU), and the Long-Acting/Extended-Release Research Resource Program (LEAP), supported by the NIH. Since 2012 he has been a member of the WHO Guidelines Panel for Treatment and Prevention of HIV in Children, Adolescents, and Adults.

Dr. Manjari Quintanar-Solares

Dr. Manjari Quintanar-Solares is a Senior Program Officer in the Medical Devices and Health Technologies Program at PATH, and leads projects related to the development, introduction, and evaluation of health technologies and associated systems in low- and middle-income country health delivery programs.

Dr. Marc Baum

Dr. Marc Baum is President, Senior Faculty, and Founder of the nonprofit organization, Oak Crest Institute of Science, an innovative chemistry and biology research and education center in Monrovia, CA. Marc earned a PhD in organic chemistry from Imperial College, London, UK. His principal biomedical research interests include development of innovative and practical drug delivery systems to combat infectious diseases; pharmacology of antiretroviral agents for HIV prophylaxis; and microbial dynamics in specialized niches.

Ms. Nakitto Aisha Gava

Ms. Nakitto Aisha Gava is a member of the IMPAACT Community Advisory Board (CAB) Leadership Group and serves as the Community Representative for the IMPAACT Treatment Scientific Committee. She is pursuing a Bachelor’s Degree in Law and is a member of the Adolescent and Youth Sub-CAB at the Baylor-Uganda Clinical Research Site in Kampala, Uganda.

Mr. Thabo Makete

Mr. Thabo Makete is a member of the IMPAACT Community Advisory Board (CAB) Leadership Group and serves as the Community Representative for the IMPAACT Treatment Scientific Committee. Mr. Makete is passionate about research for treatment solutions for HIV and TB, GBV/IPV, COVID-19, and other sectors of health and social development. Mr. Makete is Chairperson of the Treatment CAB at the Wits RHI Shandukani Clinical Research Site in Johannesburg, South Africa.